Moderna begins 3rd stage of trial for potential COVID-19 vaccine

Moderna begins 3rd stage of trial for potential COVID-19 vaccine

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Moderna begins 3rd stage of trial for potential COVID-19 vaccine

Washington: Drugmaker Moderna said Monday it has begun a 30,000-patient, third-stage clinical trial for its COVID-19 vaccine candidate — a day after receiving an additional $472 million from the U.S. government.

Called the COVE, or Coronavirus Efficacy, study, the trial is being performed at 100 clinical research sites in collaboration with the National Institute of Allergy and Infectious Diseases and the U.S. Biomedical Advanced Research and Development Authority, or BARDA.

Moderna said it has begun dosing human participants.

“We are grateful to the efforts of so many inside and outside the company to get us to this important milestone,” Moderna CEO Stephane Bancel said in a statement.

“We look forward to this trial demonstrating the potential of our vaccine to prevent COVID-19, so that we can defeat this pandemic.”

Moderna said Sunday it received the new federal funding to support late-stage clinical development as part of the Trump administration’s Operation Warp Speed initiative to find a COVID-19 vaccine.

BARDA has so far allocated nearly $1 billion in total funding to Moderna for its vaccine candidate, mRNA-1273. Phase 1 trial results showed the vaccine spurred antibody reactions in all 45 participants, with no serious side-effects, following two injections over the course of four weeks.

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